Multiple Chemical Sensitivity (MCS): History, Epidemiology and Mechanism

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Research on Multiple Chemical Sensitivity ( MCS )

This document lists citations for peer-reviewed journal articles that support a physiological basis for MCS. Disruption of the blood-brain barrier and neuronal cell death in cingulate cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome. combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alt...

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The German Multicentre Study on Multiple Chemical Sensitivity (MCS).

In this multicentre study on multiple chemical sensitivity (MCS) 291 consecutive environmental medicine (EM) outpatients were examined in several environmental medicine outpatient centres/units throughout Germany in 2000/2003. Of the EM outpatients, 89 were male (30.6%) and 202 were female (69.4%), aged 22-80 (mean 48 years, S.D.=12 years). The sample was representative for university-based env...

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Clinical characteristics of chemical sensitivity: an illustrative case history of asthma and MCS.

A case history of the induction of asthma and chemical sensitivity in a 42-year-old registered nurse illustrates several of the characteristic features of multiple chemical sensitivity (MCS). This patient's problems started shortly after moving into a new home under construction, with associated chemical exposures. Other MCS patients report the onset of the condition with other chemical exposur...

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Multiple Chemical Sensitivity: Toxicological and Sensitivity Mechanisms

Cases of multiple chemical sensitivity (MCS) are reported to be initiated by seven classes of chemicals. Each of the seven acts along a specific pathway, indirectly producing increases in NMDA activity in the mammalian body. Members of each of these seven classes have their toxicant responses lowered by NMDA antagonists, showing that the NMDA response is important for the toxic actions of these...

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Olfaction and multiple chemical sensitivity.

In this paper, a description of olfactory anatomy is presented, followed by a brief review of modern procedures for testing olfactory function. Information from the sole study which has quantitatively examined olfactory function in patients with apparent multiple chemical sensitivity (MCS) is presented. In essence, this study suggests that MCS is associated with increased nasal airflow resistan...

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ژورنال

عنوان ژورنال: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)

سال: 2018

ISSN: 0021-5082,1882-6482

DOI: 10.1265/jjh.73.1